Maria Flemming is a witch, the wife of Carson Flemming, and the mother of Isobel Flemming and Lilith Labonair. She is also the grandmother of Arielle Labonair and Hayley Marshall as well as Elena and Alexandria Gilbert. Logan Labonair was her son-in-law due to marrying Lilith and Alaric Saltzman is her former son-in-law due to marrying Isobel before she died.
Through their marriages to Elena and Alexandria, Damon Salvatore and Niklaus Mikaelson are her grandson-in-laws and Stefan Salvatore is her former grandson-in-law. She is also the great-grandmother of Hope, Jaxon, Nikolina, Lillian, Grayson, Sarah, Miranda, Jenna, Stefanie, and Nik.