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Notice: This article uses content directly taken from the Werewolf Venom article at the Vampire Diaries Wiki, and is licensed under the Creative Commons Attribution-Share Alike License.

Werewolf Venom is an ability of werewolves and vampire-werewolf hybrids to generate an extremely deadly toxin that is fatal to vampires and harmful to Original vampires. It is secreted through their fangs which allow them to be transferred through a bite.

They are produced by the salivary glands found in mouths of both werewolves and hybrids and is usually used as a weapon against their vampire enemies, as one of the easiest methods of killing a vampire.

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